<?xml version="1.0" encoding="UTF-8"?>
<obo>
  <source>
    <source_type>file</source_type>
    <source_path>gene_ontology.obo</source_path>
    <source_md5>c57a77d3c092e3e737dd9fa551132708</source_md5>
    <source_mtime>1109667825</source_mtime>
  </source>
  <header>
    <format-version>1.0</format-version>
    <date>25:02:2005 15:42</date>
    <saved-by>midori</saved-by>
    <auto-generated-by>DAG-Edit 1.419 rev 3</auto-generated-by>
    <default-namespace>gene_ontology</default-namespace>
    <remark>cvs version: $Revision: 1.2 $</remark>
    <subsetdef>
      <id>goslim_goa</id>
      <name>GOA and proteome slim</name>
    </subsetdef>
    <subsetdef>
      <id>goslim_yeast</id>
      <name>Yeast GO slim</name>
    </subsetdef>
    <subsetdef>
      <id>goslim_plant</id>
      <name>Plant GO slim</name>
    </subsetdef>
    <subsetdef>
      <id>goslim_generic</id>
      <name>Generic GO slim</name>
    </subsetdef>
    <subsetdef>
      <id>gosubset_prok</id>
      <name>Prokaryotic GO subset</name>
    </subsetdef>
  </header>
  <term>
    <id>GO:0000001</id>
    <name>mitochondrion inheritance</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.</defstr>
      <dbxref>
        <acc>11389764</acc>
        <dbname>PMID</dbname>
      </dbxref>
      <dbxref>
        <acc>10873824</acc>
        <dbname>PMID</dbname>
      </dbxref>
      <dbxref>
        <acc>mcc</acc>
        <dbname>SGD</dbname>
      </dbxref>
    </def>
    <is_a>GO:0048308</is_a>
    <is_a>GO:0048311</is_a>
    <comment>A comment added for unit testing</comment>
  </term>
  <term>
    <id>GO:0000002</id>
    <name>mitochondrial genome maintenance</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>The maintenance of the structure and integrity of the mitochondrial genome.</defstr>
      <dbxref>
        <acc>ai</acc>
        <dbname>GO</dbname>
      </dbxref>
    </def>
    <is_a>GO:0007005</is_a>
  </term>
  <term>
    <id>GO:0000003</id>
    <name>reproduction</name>
    <alt_id>GO:0019952</alt_id>
    <namespace>biological_process</namespace>
    <def>
      <defstr>The production by an organism of new individuals that contain some portion of their genetic material inherited from that organism.</defstr>
      <dbxref>
        <acc>0198506732</acc>
        <dbname>ISBN</dbname>
      </dbxref>
      <dbxref>
        <acc>curators</acc>
        <dbname>GO</dbname>
      </dbxref>
    </def>
    <subset>goslim_generic</subset>
    <subset>goslim_plant</subset>
    <subset>gosubset_prok</subset>
    <is_a>GO:0007275</is_a>
  </term>
  <term>
    <id>GO:0000004</id>
    <name>biological_process unknown</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>Used for the annotation of gene products whose process is not known or cannot be inferred.</defstr>
      <dbxref>
        <acc>curators</acc>
        <dbname>SGD</dbname>
      </dbxref>
    </def>
    <subset>goslim_generic</subset>
    <subset>goslim_goa</subset>
    <subset>goslim_plant</subset>
    <subset>goslim_yeast</subset>
    <subset>gosubset_prok</subset>
    <is_a>GO:0008150</is_a>
  </term>
  <term>
    <id>GO:0000005</id>
    <name>ribosomal chaperone activity</name>
    <namespace>molecular_function</namespace>
    <def>
      <defstr>OBSOLETE. Assists in the correct assembly of ribosomes or ribosomal subunits in vivo, but is not a component of the assembled ribosome when performing its normal biological function.</defstr>
      <dbxref>
        <acc>jl</acc>
        <dbname>GO</dbname>
      </dbxref>
      <dbxref>
        <acc>12150913</acc>
        <dbname>PMID</dbname>
      </dbxref>
    </def>
    <comment>This term was made obsolete because it refers to a class of gene products and a biological process rather than a molecular function. To update annotations, consider the molecular function term 'unfolded protein binding ; GO\:0051082' and the biological process term 'ribosome biogenesis and assembly ; GO\:0042254' and its children.</comment>
    <is_obsolete>1</is_obsolete>
  </term>
  <term>
    <id>GO:0000006</id>
    <name>high affinity zinc uptake transporter activity</name>
    <namespace>molecular_function</namespace>
    <def>
      <defstr>Catalysis of the reaction: Zn2+(out) = Zn2+(in), probably powered by proton motive force.</defstr>
      <dbxref>
        <acc>2.A.5.1.1</acc>
        <dbname>TC</dbname>
      </dbxref>
    </def>
    <xref_analog>
      <acc>2.A.5.1.1</acc>
      <dbname>TC</dbname>
    </xref_analog>
    <is_a>GO:0005385</is_a>
  </term>
  <term>
    <id>GO:0000007</id>
    <name>low-affinity zinc ion transporter activity</name>
    <namespace>molecular_function</namespace>
    <is_a>GO:0005385</is_a>
  </term>
  <term>
    <id>GO:0000008</id>
    <name>thioredoxin</name>
    <alt_id>GO:0000013</alt_id>
    <namespace>molecular_function</namespace>
    <def>
      <defstr>OBSOLETE. A small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. Interacts with a broad range of proteins by a redox mechanism, based on the reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol.</defstr>
      <dbxref>
        <acc>kd</acc>
        <dbname>SP</dbname>
      </dbxref>
    </def>
    <comment>This term was made obsolete because it represents gene products. To update annotations, consider the molecular function term 'thiol-disulfide exchange intermediate activity ; GO\:0030508'.</comment>
    <is_obsolete>1</is_obsolete>
  </term>
  <term>
    <id>GO:0000009</id>
    <name>alpha-1,6-mannosyltransferase activity</name>
    <namespace>molecular_function</namespace>
    <def>
      <defstr>Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,6-linkage.</defstr>
      <dbxref>
        <acc>mcc</acc>
        <dbname>SGD</dbname>
      </dbxref>
      <dbxref>
        <acc>2644248</acc>
        <dbname>PMID</dbname>
      </dbxref>
    </def>
    <xref_analog>
      <acc>2.4.1.-</acc>
      <dbname>EC</dbname>
    </xref_analog>
    <is_a>GO:0000030</is_a>
  </term>
  <term>
    <id>GO:0000010</id>
    <name>trans-hexaprenyltranstransferase activity</name>
    <namespace>molecular_function</namespace>
    <def>
      <defstr>Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = diphosphate + all-trans-heptaprenyl diphosphate.</defstr>
      <dbxref>
        <acc>2.5.1.30</acc>
        <dbname>EC</dbname>
      </dbxref>
    </def>
    <subset>gosubset_prok</subset>
    <xref_analog>
      <acc>2.5.1.30</acc>
      <dbname>EC</dbname>
    </xref_analog>
    <xref_analog>
      <acc>TRANS-HEXAPRENYLTRANSTRANSFERASE-RXN</acc>
      <dbname>MetaCyc</dbname>
    </xref_analog>
    <is_a>GO:0016765</is_a>
  </term>
  <term>
    <id>GO:0000011</id>
    <name>vacuole inheritance</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.</defstr>
      <dbxref>
        <acc>14616069</acc>
        <dbname>PMID</dbname>
      </dbxref>
      <dbxref>
        <acc>10873824</acc>
        <dbname>PMID</dbname>
      </dbxref>
      <dbxref>
        <acc>mcc</acc>
        <dbname>SGD</dbname>
      </dbxref>
    </def>
    <is_a>GO:0007033</is_a>
    <is_a>GO:0048308</is_a>
  </term>
  <term>
    <id>GO:0000012</id>
    <name>single strand break repair</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.</defstr>
      <dbxref>
        <acc>//www.ultranet.com/~jkimball/BiologyPages/D/DNArepair.html</acc>
        <dbname>http</dbname>
      </dbxref>
    </def>
    <subset>gosubset_prok</subset>
    <is_a>GO:0006281</is_a>
  </term>
  <term>
    <id>GO:0000014</id>
    <name>single-stranded DNA specific endodeoxyribonuclease activity</name>
    <namespace>molecular_function</namespace>
    <def>
      <defstr>Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.</defstr>
      <dbxref>
        <acc>mah</acc>
        <dbname>GO</dbname>
      </dbxref>
    </def>
    <is_a>GO:0004520</is_a>
  </term>
  <term>
    <id>GO:0000015</id>
    <name>phosphopyruvate hydratase complex</name>
    <namespace>cellular_component</namespace>
    <def>
      <defstr>A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.</defstr>
      <dbxref>
        <acc>0198506732</acc>
        <dbname>ISBN</dbname>
      </dbxref>
      <dbxref>
        <acc>jl</acc>
        <dbname>GO</dbname>
      </dbxref>
    </def>
    <subset>gosubset_prok</subset>
    <synonym scope="exact">
      <synonym_text>enolase complex</synonym_text>
    </synonym>
    <is_a>GO:0043234</is_a>
    <relationship>
      <type>part_of</type>
      <to>GO:0005829</to>
    </relationship>
  </term>
  <term>
    <id>GO:0000016</id>
    <name>lactase activity</name>
    <namespace>molecular_function</namespace>
    <def>
      <defstr>Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.</defstr>
      <dbxref>
        <acc>3.2.1.108</acc>
        <dbname>EC</dbname>
      </dbxref>
    </def>
    <xref_analog>
      <acc>3.2.1.108</acc>
      <dbname>EC</dbname>
    </xref_analog>
    <xref_analog>
      <acc>LACTASE-RXN</acc>
      <dbname>MetaCyc</dbname>
    </xref_analog>
    <is_a>GO:0004553</is_a>
  </term>
  <term>
    <id>GO:0000017</id>
    <name>alpha-glucoside transport</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>The directed movement of alpha-glucosides into, out of, within or between cells. Alpha-glucosides are glycosides in which the sugar moiety is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.</defstr>
      <dbxref>
        <acc>jl</acc>
        <dbname>GO</dbname>
      </dbxref>
      <dbxref>
        <acc>0198506732</acc>
        <dbname>ISBN</dbname>
      </dbxref>
      <dbxref>
        <acc>//www.biochem.purdue.edu/</acc>
        <dbname>http</dbname>
      </dbxref>
    </def>
    <is_a>GO:0042946</is_a>
  </term>
  <term>
    <id>GO:0000018</id>
    <name>regulation of DNA recombination</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>Any process that modulates the frequency, rate or extent of DNA recombination, the processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.</defstr>
      <dbxref>
        <acc>curators</acc>
        <dbname>GO</dbname>
      </dbxref>
      <dbxref>
        <acc>0198506732</acc>
        <dbname>ISBN</dbname>
      </dbxref>
    </def>
    <subset>gosubset_prok</subset>
    <is_a>GO:0051052</is_a>
    <relationship>
      <type>part_of</type>
      <to>GO:0006310</to>
    </relationship>
  </term>
  <term>
    <id>GO:0000019</id>
    <name>regulation of mitotic recombination</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.</defstr>
      <dbxref>
        <acc>curators</acc>
        <dbname>GO</dbname>
      </dbxref>
    </def>
    <is_a>GO:0000018</is_a>
    <relationship>
      <type>part_of</type>
      <to>GO:0006312</to>
    </relationship>
  </term>
  <term>
    <id>GO:0000020</id>
    <name>negative regulation of recombination within rDNA repeats</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>OBSOLETE. Any process that stops, prevents or reduces the rate of genetic recombination within the DNA of the genes coding for ribosomal RNA.</defstr>
      <dbxref>
        <acc>0198506732</acc>
        <dbname>ISBN</dbname>
      </dbxref>
      <dbxref>
        <acc>curators</acc>
        <dbname>GO</dbname>
      </dbxref>
    </def>
    <comment>This term was made obsolete because it describes a substrate-specific process. To update annotations, consider the biological process term 'negative regulation of mitotic recombination ; GO\:0045950'.</comment>
    <is_obsolete>1</is_obsolete>
  </term>
  <term>
    <id>GO:0000022</id>
    <name>mitotic spindle elongation</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>Lengthening of the distance between poles of the mitotic spindle.</defstr>
      <dbxref>
        <acc>mah</acc>
        <dbname>SGD</dbname>
      </dbxref>
    </def>
    <synonym scope="exact">
      <synonym_text>spindle elongation during mitosis</synonym_text>
    </synonym>
    <is_a>GO:0051231</is_a>
    <relationship>
      <type>part_of</type>
      <to>GO:0007052</to>
    </relationship>
  </term>
  <term>
    <id>GO:0000023</id>
    <name>maltose metabolism</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>The chemical reactions involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.</defstr>
      <dbxref>
        <acc>0198506732</acc>
        <dbname>ISBN</dbname>
      </dbxref>
      <dbxref>
        <acc>jl</acc>
        <dbname>GO</dbname>
      </dbxref>
    </def>
    <subset>gosubset_prok</subset>
    <synonym scope="exact">
      <synonym_text>malt sugar metabolism</synonym_text>
    </synonym>
    <is_a>GO:0005984</is_a>
  </term>
  <term>
    <id>GO:0000024</id>
    <name>maltose biosynthesis</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>The formation from simpler components of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).</defstr>
      <dbxref>
        <acc>jl</acc>
        <dbname>GO</dbname>
      </dbxref>
      <dbxref>
        <acc>0198506732</acc>
        <dbname>ISBN</dbname>
      </dbxref>
    </def>
    <subset>gosubset_prok</subset>
    <synonym scope="exact">
      <synonym_text>malt sugar biosynthesis</synonym_text>
    </synonym>
    <is_a>GO:0000023</is_a>
    <is_a>GO:0046351</is_a>
  </term>
  <term>
    <id>GO:0000025</id>
    <name>maltose catabolism</name>
    <namespace>biological_process</namespace>
    <def>
      <defstr>The breakdown into simpler components of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).</defstr>
      <dbxref>
        <acc>0198506732</acc>
        <dbname>ISBN</dbname>
      </dbxref>
      <dbxref>
        <acc>jl</acc>
        <dbname>GO</dbname>
      </dbxref>
    </def>
    <subset>gosubset_prok</subset>
    <synonym scope="exact">
      <synonym_text>malt sugar catabolism</synonym_text>
    </synonym>
    <xref_analog>
      <acc>MALTOSECAT-PWY</acc>
      <dbname>MetaCyc</dbname>
    </xref_analog>
    <is_a>GO:0000023</is_a>
    <is_a>GO:0046352</is_a>
  </term>
  <term>
    <id>GO:0000026</id>
    <name>alpha-1,2-mannosyltransferase activity</name>
    <namespace>molecular_function</namespace>
    <def>
      <defstr>Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage.</defstr>
      <dbxref>
        <acc>mcc</acc>
        <dbname>SGD</dbname>
      </dbxref>
      <dbxref>
        <acc>10521541</acc>
        <dbname>PMID</dbname>
      </dbxref>
    </def>
    <xref_analog>
      <acc>2.4.1.-</acc>
      <dbname>EC</dbname>
    </xref_analog>
    <is_a>GO:0000030</is_a>
  </term>
</obo>
