# Copyright © 1996-2007 SRI International, Marine Biological Laboratory, DoubleTwist Inc., The Institute for Genomic Research, J. Craig Venter Institute, University of California at San Diego, and UNAM.  All Rights Reserved.
#
#
# Please see the license agreement regarding the use of and distribution of this file.
# The format of this file is defined at http://bioinformatics.ai.sri.com/ptools/flatfile-format.html .
#
# Species: E. coli K-12
# Database: EcoCyc
# Version: 11.5
# File Name: pathways.dat
# Date and time generated: August 6, 2007, 17:31:26
#
UNIQUE-ID - SULFATE-CYS-PWY
TYPES - Super-Pathways
COMMON-NAME - superpathway of sulfate assimilation and cysteine biosynthesis
PATHWAY-LINKS - (G3P GLYCOLYSIS)
PREDECESSORS - (SERINE-O-ACETTRAN-RXN RXN0-5114)
PREDECESSORS - SERSYN-PWY
PREDECESSORS - CYSTSYN-PWY
PREDECESSORS - SO4ASSIM-PWY
PREDECESSORS - (ACSERLY-RXN SULFITE-REDUCT-RXN)
REACTION-LAYOUT - (SERSYN-PWY (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LAYOUT - (CYSTSYN-PWY (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LAYOUT - (SO4ASSIM-PWY (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LIST - SERSYN-PWY
REACTION-LIST - CYSTSYN-PWY
REACTION-LIST - SO4ASSIM-PWY
SUB-PATHWAYS - SERSYN-PWY
SUB-PATHWAYS - CYSTSYN-PWY
SUB-PATHWAYS - SO4ASSIM-PWY
//
UNIQUE-ID - PWY0-781
TYPES - Super-Pathways
COMMON-NAME - aspartate superpathway
PREDECESSORS - (S-ADENMETSYN-RXN HOMOCYSMETB12-RXN)
PREDECESSORS - (S-ADENMETSYN-RXN HOMOCYSMET-RXN)
PREDECESSORS - (L-ASPARTATE-OXID-RXN ASPAMINOTRANS-RXN)
PREDECESSORS - PYRIDNUCSYN-PWY
PREDECESSORS - (ASPARTATEKIN-RXN ASPAMINOTRANS-RXN)
PREDECESSORS - P4-PWY
PREDECESSORS - ASPARTATESYN-PWY
REACTION-LAYOUT - (PYRIDNUCSYN-PWY (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LAYOUT - (P4-PWY (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LAYOUT - (ASPARTATESYN-PWY (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LIST - PYRIDNUCSYN-PWY
REACTION-LIST - P4-PWY
REACTION-LIST - ASPARTATESYN-PWY
SUB-PATHWAYS - PYRIDNUCSYN-PWY
SUB-PATHWAYS - P4-PWY
SUB-PATHWAYS - ASPARTATESYN-PWY
//
UNIQUE-ID - PRPP-PWY
TYPES - Super-Pathways
COMMON-NAME - superpathway of histidine, purine, and pyrimidine biosynthesis
COMMENT - Pyrimidine, purine, and pyridine nucleotide synthesis all require phosphoribosylpyrophosphate (PRPP) as a precursor.  PRPP is utilized by both the de novo pathways and the auxiliary or salvage pathways by which endogenously formed or exogenously added pyrimidine, purine, or pyridine bases are converted to the corresponding ribonucleoside monophosphates by phosphoribosyltransferases. PRPP is also used in the histidine and tryptophan biosynthesis pathways.  PRPP thus may be regarded as a precursor for the synthesis of nucleic acids, proteins, and for the NAD(P) coenzymes.The formation of PRPP therefore is subjected to strict metabolic control. |CITS:[86196114]|
PREDECESSORS - (ATPPHOSPHORIBOSYLTRANS-RXN RXN0-1401)
PREDECESSORS - (OROPRIBTRANS-RXN RXN0-1401)
PREDECESSORS - (PRPPAMIDOTRANS-RXN RXN0-1401)
PREDECESSORS - PWY0-661
PREDECESSORS - PWY0-162
PREDECESSORS - DENOVOPURINE2-PWY
PREDECESSORS - HISTSYN-PWY
PREDECESSORS - PWY0-662
PREDECESSORS - (PRPPAMIDOTRANS-RXN PRPPSYN-RXN)
PREDECESSORS - (OROPRIBTRANS-RXN PRPPSYN-RXN)
PREDECESSORS - (ATPPHOSPHORIBOSYLTRANS-RXN PRPPSYN-RXN)
PRIMARIES - (OROPRIBTRANS-RXN (OROTATE PRPP))
REACTION-LAYOUT - (PWY0-661 (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LAYOUT - (PWY0-662 (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LAYOUT - (PWY0-162 (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LAYOUT - (DENOVOPURINE2-PWY (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LAYOUT - (HISTSYN-PWY (:LEFT-PRIMARIES) (:DIRECTION NIL) (:RIGHT-PRIMARIES))
REACTION-LIST - PWY0-661
REACTION-LIST - PWY0-662
REACTION-LIST - PWY0-162
REACTION-LIST - DENOVOPURINE2-PWY
REACTION-LIST - HISTSYN-PWY
SUB-PATHWAYS - PWY0-661
SUB-PATHWAYS - PWY0-662
SUB-PATHWAYS - PWY0-162
SUB-PATHWAYS - DENOVOPURINE2-PWY
SUB-PATHWAYS - HISTSYN-PWY
//