Pathway Tools System Requirements

• Operating System
  • Linux on any AMD or Intel-based x86_64 system that uses a version 2.2 or higher kernel and glibc 2.11+
    Known to work on:
    • The Redhat family, including Fedora 13+, RHEL6+, and CentOS 6+.
    • Debian Linux, version 6+ and Ubuntu derivatives. It works on Ubuntu-10.04 and later.
    Known Linux problems:
    • On Suse-8.2 on a x86_64 system, one user reported that restarting the WWW server mode of Pathway Tools by means of automated scripts never worked. The problem does not seem to occur on Suse-8.1 .
    Requires X11 libraries installed. See detailed installation instructions below.

  • MacOS X 10.8, 10.9, 10.10, 10.11

  • Microsoft Windows (64-bit only) XP, Vista, and Windows 7. Note that as of now, we have only tested on Windows 7 64-bit.
    Requires Microsoft Visual C++ Redistributable Package to be installed. Installer will prompt for permission if not installed. 32-bit Windows is no longer supported.

• Hardware
  • Processor: Minimum requirement = 1 GHz
    • Linux-64 executables will only run on a Linux x86_64 machine.

  • Memory (RAM) recommended. Generally, we recommend that the machine on which you run these images have an amount of RAM of at least the executable size. Adding more memory than the recommended amounts will increase performance. We only recommend using the Tiers 1+2+3 version if you are planning to do large-scale analyses.
    • Tier 1 (2 PGDBs, EcoCyc and MetaCyc): 4GB (recommend 6+ GB)
    • Tiers 1+2 (around 15 PGDBs): 6GB (recommend 8+ GB)
    • Tiers 1+2+3 (64-bit 3+GHz CPU required): 12 GB (recommend 16+ GB)
      NOTE: For Tier1+2+3, you need to tweak two user/system parameters (see your OS docs for exact parameter names):
      • max open files should be bumped up to at least 8k for the userid running the web server.
      • stack size limit should be bumped up to at least 8MB

  • Swap space of your operating system should be configured to accommodate your RAM space.

  • Disk space: Minimum requirement ranges from 1.5+ GB (Tier 1 DBs only) to 130 GB (Tiers 1+2+3 DBs)
  • For Web server mode, it's recommended that you clear out the files in /tmp after a version upgrade.
    /tmp should have at least 32GB of free space for web server operation.